Targefect siRNA Citations    

References citing use of targefect siRNA :

Targefect siRNA references  (Gene Silencing)

1.Boris A Hesser, Xiao Huan Liang, Gieri Camenisch, Suya Yang, David Lewin, Richard Scheller, Napoleone Ferrara, and Hans-Peter Gerber (2004)  Down syndrome critical region protein1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells.  Blood,  10.1182/blood-2004-01-0273.

(HDMVECs) Human Dermal microvascular endothelial cells

2. Partovian C, Simons M (2004) Regulation of protein kinase B/Akt activity and Ser(473) phosphorylation by protein kinase Calpha in endothelial cells.
Cell Signal. 2004 Aug;16(8):951-7.

3. Radu V. Stan, Eugene Tkachenko, and Ingrid R. Niesman (2004) PV1 Is a Key Structural Component for the Formation of the Stomatal and Fenestral Diaphragms

Mol. Biol. Cell published online May 21, 2004, 10.1091/mbc.E03-08-0593

HUVECs (Human umbilical vein endothelial cells), HEK-293, Cos-7 , Hela

4. Radu V. Stan. Multiple PV1 dimers reside in the same stomatal or fenestral diaphragm
Am J Physiol Heart Circ Physiol, Apr 2004; 286: 1347 - 1353.

5.  Jiaping Wu, Cherie Parungo, Guifu Wu, Peter M. Kang, Roger J. Laham, Frank W. Sellke, Michael Simons, and Jian Li  (2004) PR39 Inhibits Apoptosis in Hypoxic Endothelial Cells: Role of Inhibitor Apoptosis Protein-2.  Circulation,  109: 1660 - 1667.

BAECs (Bovine aortic endothelial cells)

6. Raquel Pluvinet, Jordi Petriz, Joan Torras, Inmaculada Herrero-Fresneda, Josep M Cruzado, Josep M Grinyo, and Josep M Aran. RNAi-mediated silencing of CD40 prevents leukocyte adhesion on CD154-activated endothelial cells. Blood, Aug 2004; 10.1182/blood-2004-03-0817.

HUVECs

7 Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky, Marc Montminy

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine10, 530 - 534 (01 May 2004) Letters

Hepatocytes

8.  Jeong Hoon Kim, Hongwei Li, and Michael R. Stallcup (2003)  CoCoA, a Nuclear Receptor Coactivator which Acts through an N-Terminal Activation Domain of p160 Coactivators
Molecular Cell 2003 12: 1537-1549
MCF-7, COS-7 

9.  C. Radel and V. Rizzo
Integrin mechanotransduction stimulates caveolin-1 phosphorylation and recruitment of Csk to mediate actin reorganization. Am J Physiol Heart Circ Physiol, Feb 2005; 288: 936 - 945.

Bovine aortic endothelial cells (BAECs)

10.  Sanjeev Choudhary, Tianlin Xiao, Leoncio A. Vergara, Sanjay Srivastava, David Nees, Joram Piatigorsky, and Naseem H. Ansari.  Role of Aldehyde Dehydrogenase Isozymes in the Defense of Rat Lens and Human Lens Epithelial Cells against Oxidative Stress.  Invest. Ophthalmol. Vis. Sci., Jan 2005; 46: 259 - 267.

HLECs (Human Lens Epithelial Cells) , rat and mouse lenses

11. Yang Luo and Glenn L. Radice (2005) N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.  J. Cell Biol., Apr 2005; 169: 29 - 34.

HUVEC, HDMVEC,

12.  Tomoaki Murakami, Hitoshi Takagi, Kiyoshi Suzuma, Izumi Suzuma, Hirokazu Ohashi, Daisuke Watanabe, Tomonari Ojima, Eri Suganami,
Masafumi Kurimoto, Hideaki Kaneto, Yoshihito Honda, and Nagahisa Yoshimura(2005)  Angiopoietin-1 Attenuates H2O2-induced SEK1/JNK
Phosphorylation through the Phosphatidylinositol 3-Kinase/Akt Pathway in Vascular Endothelial Cells, J. Biol. Chem., Sep 2005; 280: 31841 - 31849.

13.  Chohreh Partovian, Zhenwu Zhuang, Karen Moodie, Michelle Lin, Noriyuki Ouchi, William C. Sessa, Kenneth Walsh, and Michael Simons(2005)PKC Activates eNOS and Increases Arterial Blood Flow In Vivo Circ. Res.,  97: 482 - 487